Yes it is worth while to greate a personalized welcome letter using information from that Affiliate Profile. This lets them know that you have taken the time to find out something about them and they are more likely to believe that you care how they do. Also this give you the ability to help them acheive their goals better, because you will know them. I look at all my new Affilitiates Profiles as well as their VP ledger to see what they are working on most and guide them from there.