Yes, it happens in people who do not understand or will not understand this business. These are mostly people who have signed up just to see what this is all about, and on the shortcut concluded that this is not for them. They blocked your e-mail and that is reason enough not to waste the time or nerves to such people. You need to move on in search of those affiliates who will love this job and who will ask for your help or advice.
Good luck!